教育背景

1992-1996 天津大学热能系取得工学学士学位

1996-1999 天津大学热能系取得工学硕士学位

1999-2003 清华大学力学系取得工学博士学位

工作经历

2003-2005 中国科学院力学研究所，博士后

2005-2007 美国普渡大学机械工程系，访问学者

2007-2010 中国科学院力学研究所，副高研究员

2010-2013 澳大利亚麦考瑞大学先进医学院，访问学者

2013-2014 澳大利亚西悉尼大学、悉尼大学，访问学者

2014-2018 清华大学医学中心，研究员

2018-2024 清华大学医学院，研究员

2024- 至今 清华大学基础医学院，研究员

研究领域概述

张宇博士的研究方向为流体力学，在过去的研究中广泛从事与工业应用相关的流体力学研究，包括：煤粉燃烧与污染物生成的数值模拟，高炉炉膛内铁水流动与腐蚀的数值模拟，风沙流起沙机理研究，脉冲管制冷的热力循环模拟，爆燃与爆轰的数值模拟，空气污染物在城市环境中扩散的数值模拟等。

自2010年起，张宇博士凝练研究方向，专注于医工结合，专注于血液流动的数值模拟和血管类医疗器械的设计与优化。血流动力学的研究包括：血管瘤破裂风险的研究，动脉瘤支架治疗结果预测，心脑血管搭桥手术的数值评估，颈动脉和冠脉狭窄的数值评估、毛细血管内血细胞的运动模拟等。在医疗器械方面，专注于人工心脏、辅助循环、心血管植介入医疗器械的评测，并且取得了多项国家发明专利。在生物电磁学方面与校内合作者一起研究大气压冷等离子体的生物医学效应，及其在杀毒灭菌、杀灭癌症细胞和促进伤口愈合方面的生物物理机制。

贡献与荣誉

2018年，经清华大学批准，张宇研究员与航天泰心科技有限公司在清华大学本部成立“清华大学（医学院）航天泰心科技有限公司人工心脏联合研究实验室”，张宇博士任实验室主任。张宇博士于2018年受邀成为“中国研究型医院学会-医工转化与健康产业融合专业委员会”委员。同年，鉴于他在城市风环境与健康研究中的成果，被悉尼大学授予“荣誉高级研究员”。2021年，张宇博士成为中国电子工程学会高级会员。张宇博士主持了航天泰心科技有限公司产品-全国产人工心脏和航天新长征医疗器械（北京）有限公司产品-全国产ECMO的实验室评估，为企业提供了高质量的科研服务。ECMO主机拿到临床注册证后，公司给清华大学校长办公室发来正式感谢信。2024年，经基础医学院批准、清华大学实验处备案、成立了“清华大学基础医学院-心血管植介入功能测试平台”，张宇博士任平台主管。

论文发表

张宇博士发表各类学术论文两百余篇，从Scopus（斯高帕斯）导出的发表文章列表如下：

Scopus: Author ID-54893906700

1.Zhu X, Zhang Y, Chen XD. Viscous flow through a thin-walled elastic hollow ellipsoid—Experiments to demonstrate a potential flowmeter. Asia-Pacific Journal of Chemical Engineering. 2023;18(4).

2.Zhao LX, Zhao HX, Chen H, Hu C, Zhang Y, Li HP. Characteristics of Portable Air Floating-Electrode Dielectric-Barrier-Discharge Plasmas Used for Biomedicine. Plasma Chemistry and Plasma Processing. 2023;43(6):1567-85.

3.Gu H, Xia Y, Zhang Y, Chen XD. Making a Soft Elastic Pulsation Pump (SEPP). Processes. 2023;11(5).

4.Zhou LX, Wang F, Zhang Y. Studies on the Effect of Swirl on Nitric-Oxide Formation in Combustion—a Selected Review. Emission Control Science and Technology. 2022;8(3-4):171-81.

5.Zhao X, Zhao L, Xu J, Li D, Li H, Li Y, Chen H, Zhang Y. Aortic valve opening in mock-loop with continuous-flow left ventricular assist device. International Journal of Artificial Organs. 2022;45(10):809-16.

6.Zhao X, Yu Y, Zhao L, Xu J, He T, Lin Z, Zhang Y. The red blood cell damage after long-term exposure to shear stresses. Journal of Artificial Organs. 2022;25(4):298-304.

7.Wang Y, Zhao L, Zheng Z, Zhang Y. Flow Resistance Analysis of Clinically Significant Portal Hypertension in Patients with Liver Cirrhosis. Canadian Journal of Gastroenterology and Hepatology. 2022;2022.

8.Li J, Fang C, Chen J, Li HP, Wang ZB, Nie QY, Guo H, Zhao X, Zhao LX, Zhang Y, Ostrikov KK. Energy exchange modulation for selective control of gas temperature and electron number density in cold atmospheric plasmas. Plasma Sources Science and Technology. 2022;31(5).

9.Keshavarzian E, Kwok KCS, Dong K, Chauhan K, Zhang Y. An experimental Investigation of stagnant air pollution dispersion around a building in a turbulent flow. Building and Environment. 2022;224.

10.Guo GZ, Yu Y, Kwok KCS, Zhang Y. Air pollutant dispersion around high-rise buildings due to roof emissions. Building and Environment. 2022;219.

11.Zhang Y, Yu Y, Kwok KCS, Yan F. CFD-based analysis of urban haze-fog dispersion—A preliminary study. Building Simulation. 2021;14(2):365-75.

12.Liu J, Yu Y, Zhu C, Zhang Y. Comparison of LBM and FVM in the estimation of LAD stenosis. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine. 2021;235(9):1058-68.

13.Li J, Zhao LX, He T, Dong WW, Yuan Y, Zhao X, Chen XY, Zhang N, Zou ZF, Zhang Y, Li HP. A novel method for estimating the dosage of cold atmospheric plasmas in plasma medical applications. Applied Sciences (Switzerland). 2021;11(23).

14.Li G, Li D, Li J, Jia YN, Zhu C, Zhang Y, Li HP. Promotion of the Wound Healing of in vivo Rabbit Wound Infected with Methicillin-Resistant Staphylococcus aureus Treated by a Cold Atmospheric Plasma Jet. IEEE Transactions on Plasma Science. 2021;49(8):2329-39.

15.Zou J, Xiao J, Zhang Y, Li C, Chen XD. Numerical simulation of the mixing process in a soft elastic reactor with bionic contractions. Chemical Engineering Science. 2020;220.

16.Liu J, Yu F, Zhang Y. MP-PIC simulation of blood cell movement through a LAD with high stenosis. Powder Technology. 2020;361:448-54.

17.Liu J, Yu F, Zhang Y. Flow resistance coefficient analysis of left anterior descending artery stenosis: A preliminary study. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine. 2020;234(1):100-9.

18.Keshavarzian E, Jin R, Dong K, Kwok KCS, Zhang Y, Zhao M. Effect of pollutant source location on air pollutant dispersion around a high-rise building. Applied Mathematical Modelling. 2020;81:582-602.

19.Ji JJ, Li HY, Wu QY, Zhang Y, Luo XW. Estimation of the turbulent viscous shear stress in a centrifugal rotary blood pump by the large eddy particle image velocimetry method. Journal of Hydrodynamics. 2020;32(3):486-96.

20.Sia SF, Zhao X, Yu Y, Zhang Y. Multiphase particle-in-cell simulation in severe internal carotid artery stenosis. Powder Technology. 2019;358:62-7.

21.Li D, Li Y, Li G, Zhang Y, Li J, Chen H. Fluorescent reconstitution on deposition of PM 2.5 in lung and extrapulmonary organs. Proceedings of the National Academy of Sciences of the United States of America. 2019;116(7):2488-93.

22.Li D, Li G, Li J, Liu ZQ, Zhang X, Zhang Y, Li HP. Promotion of Wound Healing of Genetic Diabetic Mice Treated by a Cold Atmospheric Plasma Jet. IEEE Transactions on Plasma Science. 2019;47(11):4848-60.

23.Li D, Li G, Chen Y, Man J, Wu Q, Zhang M, Chen H, Zhang Y. The impact of erythrocytes injury on blood flow in bionic arteriole with stenosis segment. Processes. 2019;7(6).

24.Li C, Xiao J, Zhang Y, Chen XD. Mixing in a soft-elastic reactor (SER): A simulation study. Canadian Journal of Chemical Engineering. 2019;97(3):676-86.

25.Zhao X, Shao Z, Zhang Y, Liu F, Liu Z, Liu Z. Ceruloplasmin in Parkinson's disease and the nonmotor symptoms. Brain and Behavior. 2018;8(6).

26.Li Y, Hu X, Li H, Zhang Y, Chen H. Investigation of cold atmospheric plasma treatment in polydimethylsiloxane microfluidic devices with a transmural method. Journal of Physics Condensed Matter. 2018;30(38).

27.Hu J, Xuan HB, Kwok KCS, Zhang Y, Yu Y. Study of wind flow over a 6 m cube using improved delayed detached Eddy simulation. Journal of Wind Engineering and Industrial Aerodynamics. 2018;179:463-74.

28.Zhao X, Shao Z, Zhang Y, Liu X, Liu Z. Diagnostic advantage of 64-slice spiral CT angiography in preoperative diagnosis of anomalous pulmonary venous connection. International Journal of Clinical and Experimental Medicine. 2017;10(12):16283-91.

29.Zhao X, Li R, Chen Y, Sia SF, Li D, Zhang Y, Liu A. Hemodynamic analysis of intracranial aneurysms using phase-contrast magnetic resonance imaging and computational fluid dynamics. Acta Mechanica Sinica/Lixue Xuebao. 2017;33(2):472-83.

30.Zhang J, Yu Y, Qu C, Zhang Y. Experimental study and numerical simulation of periodic bubble formation at submerged micron-sized nozzles with constant gas flow rate. Chemical Engineering Science. 2017;168:1-10.

31.Yu Y, Kwok KCS, Liu XP, Zhang Y. Air pollutant dispersion around high-rise buildings under different angles of wind incidence. Journal of Wind Engineering and Industrial Aerodynamics. 2017;167:51-61.

32.Li D, Wu Q, Liu S, Chen Y, Chen H, Ruan Y, Zhang Y. Lactic Dehydrogenase in the In Vitro Evaluation of Hemolytic Properties of Ventricular Assist Device. Artificial Organs. 2017;41(11):E274-E84.

33.Li D, Wu Q, Ji J, Liu S, Zhang M, Zhang Y. Hemolysis in a continuous-flow ventricular assist device with/without chamfer. Advances in Mechanical Engineering. 2017;9(4):1-10.

34.Keshavarzian E, Jin R, Dong K, Kwok KCS, Zhang Y, editors. Impact of location of pollutant sources on air pollution dispersion around a high rise building. 9th Asia Pacific Conference on Wind Engineering, APCWE 2017; 2017.

35.Zhao M, Cui Z, Kwok K, Zhang Y. Wake-induced vibration of a small cylinder in the wake of a large cylinder. Ocean Engineering. 2016;113:75-89.

36.Sia SF, Zhao X, Li R, Zhang Y, Chong W, He L, Chen Y. Evaluation of the carotid artery stenosis based on minimization of mechanical energy loss of the blood flow. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine. 2016;230(11):1051-8.

37.Chen Y, Li R, Zhao X, Li D, Xu W, Liu A, Sia SF, Chong W, Zhang Y. Medical image based hemodynamic analysis. Advances in Mechanics. 2016;46(1):323-42.

38.Zhang Y, Kwok KCS, Liu XP, Niu JL. Characteristics of air pollutant dispersion around a high-rise building. Environmental Pollution. 2015;204:280-8.

39.Hu P, Qian Y, Zhang Y, Zhang HQ, Li Y, Chong W, Ling F. Blood flow reduction of covered small side branches after flow diverter treatment: A computational fluid hemodynamic quantitative analysis. Journal of Biomechanics. 2015;48(6):895-8.

40.Hu G, Tse KT, Kwok KCS, Zhang Y. Large eddy simulation of flow around an inclined finite square cylinder. Journal of Wind Engineering and Industrial Aerodynamics. 2015;146:172-84.

41.Zhu FP, Zhang Y, Higurashi M, Xu B, Gu YX, Mao Y, Morgan MK, Qian Y. Haemodynamic analysis of vessel remodelling in STA-MCA bypass for Moyamoya disease and its impact on bypass patency. Journal of Biomechanics. 2014;47(8):1800-5.

42.Zhang Y, Zhao M, Kwok KCS, Liu MM. Computational fluid dynamics-discrete element method analysis of the onset of scour around subsea pipelines. Applied Mathematical Modelling. 2014;39(23-24):7611-9.

43.Sia SF, Zhang Y, Qian Y, Kadir KAA, Nor HM, Morgan MK. Hemodynamic effects resulting from a common carotid to middle cerebral bypass with varying degrees of proximal internal carotid stenosis. Neurology Asia. 2014;19(3):241-7.

44.Chong W, Zhang Y, Qian Y, Lai L, Parker G, Mitchell K. Computational hemodynamics analysis of intracranial aneurysms treated with flow diverters: Correlation with clinical outcomes. American Journal of Neuroradiology. 2014;35(1):136-42.

45.Zhang Y, Takao H, Murayama Y, Qian Y. Propose a wall shear stress divergence to estimate the risks of intracranial aneurysm rupture. The Scientific World Journal. 2013;2013.

46.Zhang Y, Furusawa T, Sia SF, Umezu M, Qian Y. Proposition of an outflow boundary approach for carotid artery stenosis CFD simulation. Computer Methods in Biomechanics and Biomedical Engineering. 2013;16(5):488-94.

47.Zhang Y, Chong W, Qian Y. Investigation of intracranial aneurysm hemodynamics following flow diverter stent treatment. Medical Engineering and Physics. 2013;35(5):608-15.

48.Uemiya N, Lee CJ, Ishihara S, Yamane F, Zhang Y, Qian Y. Analysis of restenosis after carotid artery stenting: Preliminary results using computational fluid dynamics based on three-dimensional angiography. Journal of Clinical Neuroscience. 2013;20(11):1582-7.

49.Sen Y, Zhang Y, Qian Y, Morgan M, editors. Investigation of image segmentation methods for intracranial aneurysm haemodynamic research. WIT Transactions on Biomedicine and Health; 2013.

50.Lee CJ, Zhang Y, Takao H, Murayama Y, Qian Y. A fluid-structure interaction study using patient-specific ruptured and unruptured aneurysm: The effect of aneurysm morphology, hypertension and elasticity. Journal of Biomechanics. 2013;46(14):2402-10.

51.Lee CJ, Zhang Y, Takao H, Murayama Y, Qian Y. The influence of elastic upstream artery length on fluid-structure interaction modeling: A comparative study using patient-specific cerebral aneurysm. Medical Engineering and Physics. 2013;35(9):1377-84.

52.Lee CJ, Uemiya N, Ishihara S, Zhang Y, Qian Y. A comparison of estimation methods for computational fluid dynamics outflow boundary conditions using patient-specific carotid artery. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine. 2013;227(6):663-71.

53.Zhang Y, Sia SF, Morgan MK, Qian Y. Flow resistance analysis of extracranial-to-intracranial (EC-IC) vein bypass. Journal of Biomechanics. 2012;45(8):1400-5.

54.Sia SF, Qian Y, Zhang Y, Morgan MK. Mean arterial pressure required for maintaining patency of extracranial-to-intracranial bypass grafts: An investigation with computational hemodynamic models-case series. Neurosurgery. 2012;71(4):826-31.

55.Zhang Y, Li Y, Yang J, Liu D. Statistical particle stress in aeolian sand movement-derivation and validation. Powder Technology. 2011;209(1-3):147-51.

56.Sen Y, Zhang Y, Qian Y, Morgan M, editors. A comparison of medical image segmentation methods for cerebral aneurysm computational hemodynamics. Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011; 2011.

57.Luo JS, Wei XL, Li S, Yu LX, Zhang Y, Li T, Li B. Experimental study on deflagration suppression of CO by injecting nitrogen in tube. Kung Cheng Je Wu Li Hsueh Pao/Journal of Engineering Thermophysics. 2011;32(SUPPL. 1):212-5.

58.Chen L, Zhang Y, Luo EC, Li T, Wei XL. CFD analysis of thermodynamic cycles in regenerator of a pulse tube refrigerator. Kung Cheng Je Wu Li Hsueh Pao/Journal of Engineering Thermophysics. 2011;32(11):1816-8.

59.Zhang Y, Yang J, Liu D, Wei X, Yu L. Sand storms: CFD analysis of Reynolds stress and collision stress of particles near sand bed. Particuology. 2010;8(4):325-31.

60.Zhang Y, Wei XL, Liu DY. CFD study of a sudden-expanding coal combustor using Euler-Euler and Euler-Lagrange models. Fuel. 2010;89(12):3643-9.

61.Zhang Y, Chen L, Zhang C, Yu L, Wei X, Ma L, Guan C. CFD analysis of pneumatic conveying in a double-tube-socket (DTS®) pipe. Applied Mathematical Modelling. 2010;34(10):3085-97.

62.Zhang L, Wei XL, Yu LX, Zhang Y, Li T, Li B. Deflagration characteristics of a preheated CO-air mixture in a duct. Baozha Yu Chongji/Explosion and Shock Waves. 2010;30(2):191-6.

63.Zhang CX, Zhang Y, McGlinchey D, Du Y, Wei X, Ma LA, Guan CS. Experimental and numerical study on power consumptions in a double-tube-socket pneumatic conveying system. Powder Technology. 2010;204(2-3):268-72.

64.Yang J, Zhang Y, Liu D, Wei X. CFD-DEM simulation of three-dimensional aeolian sand movement. Science China: Physics, Mechanics and Astronomy. 2010;53(7):1306-18.

65.Luo J, Wei X, Li S, Yu L, Zhang Y, Li T, Li B. Study on peak overpressure and flame propagation speed of gas deflagration in the tube with obstacles. Science China Technological Sciences. 2010;53(7):1847-54.

66.Chen L, Zhang Y, Luo E, Li T, Wei X. CFD analysis of thermodynamic cycles in a pulse tube refrigerator. Cryogenics. 2010;50(11-12):743-9.

67.Zhang Y, Yu L, Wei X, Li T, Li B. Numerical and experimental investigation on the prevention of CO deflagration. Journal of Loss Prevention in the Process Industries. 2009;22(2):169-75.

68.Zhang Y, Chen L, Wei X, editors. New methodology for the estimation of energy consumption in a DOUBLE-TUBE-SOCKET (DTS®) pneumatic conveying. Proceeding of International Conference on Power Engineering, ICOPE 2009; 2009.

69.Guan CS, Zhang CX, Chen L, Wei XL, Ma LA, Zhang Y. Numerical simulation and estimation of energy consumption for the pneumatic conveying using double-tube socket. Guocheng Gongcheng Xuebao/The Chinese Journal of Process Engineering. 2009;9(4):625-33.

70.Zhang Y, Deshpande R, Huang D, Chaubal P, Zhou CQ. Numerical analysis of blast furnace hearth inner profile by using CFD and heat transfer model for different time periods. International Journal of Heat and Mass Transfer. 2008;51(1-2):186-97.

71.Zhang Y, Deshpande R, Huang D, Chaubal P, Zhou CQ, editors. Prediction of the inner profile of a blast furnace hearth. AISTech - Iron and Steel Technology Conference Proceedings; 2007.

72.Zhang Y, Deshpande R, Huang D, Chaubal P, Zhou CQ. A methodology for blast furnace hearth inner profile analysis. Journal of Heat Transfer. 2007;129(12):1729-31.

73.Zhang CX, Zhang Y, Wei XL, Sheng HZ, Tian WD. Experimental and numerical research on the particles movement in the internally circulating fluidized bed. Ranshao Kexue Yu Jishu/Journal of Combustion Science and Technology. 2007;13(2):157-62.

74.Roldan D, Zhang Y, Deshpande R, Zhou CQ, Huang D, Chaubal P. Three-dimensional CFD analysis for blast furnace hearth wear. Iron and Steel Technology. 2007;4(3):43-50.

75.Huang D, Zhang Y, Deshpande R, Chaubal P, Zhou CQ, editors. Simulation of the hearth draining process and thermal stress of a BF hearth. AISTech - Iron and Steel Technology Conference Proceedings; 2007.

76.Zhang Y, Zhou LX, Wei XL, Sheng HZ. Studies of the effect of a coal concentrator on NO formation in swirling coal combustion. International Journal of Heat and Mass Transfer. 2006;49(1-2):421-6.

77.Zhang Y, Deshpande R, Huang D, Chaubal P, Zhou CQ, editors. A methodology for blast furnace hearth wear analysis. American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD; 2006.

78.Roldan D, Zhang Y, Deshpande R, Huang D, Chaubal P, Zhou CQ, editors. 3-D CFD analysis for blast furnace hearth wear. AISTech - Iron and Steel Technology Conference Proceedings; 2006.

79.Huang D, Zhang Y, Deshpande R, Chaubal P, Zhou CQ, editors. 3-D blast furnace hearth model and its application. 4th International Congress on the Science and Technology of Ironmarking, ICSTI 2006, Proceedings; 2006.

80.Zhang Y, Zhou L, Wei X, Sheng H. Numerical simulation of NOx, formation in coal combustion with inlet natural gas burning. Chinese Journal of Chemical Engineering. 2005;13(3):318-23.

81.Zhang Y, Wei XL, Zhou LX, Sheng HZ. Simulation of coal combustion by AUSM turbulence-chemistry char combustion model and a full two-fluid model. Fuel. 2005;84(14-15):1798-804.

82.Zhang Y, Zhou LX, Zhang J. PDPA studies on the effect of blockings and concentrators to the turbulence and particle concentration in a swirl burner. Kung Cheng Je Wu Li Hsueh Pao/Journal of Engineering Thermophysics. 2004;25(5):867-70.

83.Zhou LX, Zhang Y, Zhang J, editors. Simulation of the effect of inlet blocking on no formation in a swirl coal combustor. Proceedings of the ASME Summer Heat Transfer Conference; 2003.

84.Zhou LX, Zhang Y, Zhang J. Simulation of swirling coal combustion using a full two-fluid model and an AUSM turbulence-chemistry model. Fuel. 2003;82(8):1001-7.

85.Zhang Y, Zhou LX, Zhang J. AUSM turbulence-chemistry model for simulating NO formation in swirling coal combustion. Ranshao Kexue Yu Jishu/Journal of Combustion Science and Technology. 2003;9(3):209-13.

86.Zhang Y, Zhou LX, Zhang J. Simulation of the effect of inlet blocking on NO formation in a swirl coal combustor. Zhongguo Dianji Gongcheng Xuebao/Proceedings of the Chinese Society of Electrical Engineering. 2003;23(9):162-6.

87.Zhang Y, Zhou L, Zhang J. Simplified Solomon pyrolysis model and simulation of no formation in swirling coal combustion. Huagong Xuebao/Journal of Chemical Industry and Engineering (China). 2003;54(9):1274-8.

88.Gu H, Chu Z, Zhu K, Zhang Y, Wang J, Zhu Q, Li X, Meng X, Yang J. Experimental investigation on the coating drying of hub and mechanism of infraread drying. Kung Cheng Je Wu Li Hsueh Pao/Journal of Engineering Thermophysics. 1999;20(6).

89.Zhu K, Chu Z, Liu J, Yang J, Zhu Q, Zhang Y, Wu S. The study of the optimization of seeds' heat and mass transfer by thermo-image and physiological experiment method. Kung Cheng Je Wu Li Hsueh Pao/Journal of Engineering Thermophysics. 1998;19(4)

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