Education and Professional Positions :
2023-至今 Assistant researcher, School of Basic Medical Sciences, Tsinghua University, Beijing, China
2020-2023 Post-doctoral, School of Medical, Tsinghua University, Beijing, China
2020-2014 Ph.D., Sichuan University,Sichuan, China
Research Areas:
My research is mainly engaged in the research of important pathogens such as influenza virus, coronavirus, herpes simplex virus and Zika virus, and has made innovative achievements. I have published several papers as first author or co-first author in Cell, Protein Cell, and JV journals, and related scientific achievements was awarded the Ten major progress of Chinese Sciences (Ministry of Science and Technology, China, 2022), Ten major scientific and technological progress of Chinese Life Sciences (Association for Science and Technology, China, 2022), Important medical progress in China (Chinese Academy of Medical Sciences, China, 2022).
Honors and Awards:
➢ Young Elite Scientists Sponsorship Program by CAST (2023)
➢ Young Elite Scientists Sponsorship Program by BAST (2022)
➢ Ten major progress of Chinese Sciences (2022)
➢ Ten major scientific and technological progress of Chinese Life Sciences, China (2022)
➢ Important medical progress in China in 2021 (2022)
Selected Publications:
(1) Liming Yan #, Yunxiang Yang #, Mingyu Li #, Ying Zhang #, Litao Zheng #, Ji Ge #, Yucen Huang #, Zhenyu Liu #, Tao Wang, Shan Gao, Ran Zhang, Yuanyun Huang, Luke W. Guddat, Yan Gao *, Zihe Rao *, and Zhiyong Lou *. Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading. Cell. 2021,184 (13), 3474-3485 e11.
(2) Yunxiang Yang #, Pan Yang #, Nan Wang, Zhonghao Chen, Zhenghong Zhou, Zihe Rao *, and Xiangxi Wang *. Architecture of the viral genome-packaging complex and implications for DNA translocation. Protein Cell. 2020, 11(5):339–351.
(3) Mengli Cheng #, Yunxiang Yang #, Fan Yang, Zhongyu Liu, Dan Wen, Pan Yang, Xingyao Huang, Haolong Dong, Yanpeng Xu, Xiaofeng Li, Yongqiang Deng, Qing Ye, Ling Zhu, Juan Li, Aihua Zheng, Weifeng Shi, Xiangxi Wang *, Chengfeng Qin *. Glycan loop deletions in the envelope protein of Asian Zika virus enhance neurovirulence and cause severe microcephaly in mice. Journal of Virology. 2022, 96(23):e0087922.
(4) Liming Yan #, Ji Ge #, Litao Zheng #, Ying Zhang, Yan Gao, Tao Wang, Yucen Huang, Yunxiang Yang, Shan Gao, Mingyu Li, Zhenyu Liu, Haofeng Wang, Yingjian Li, Yu Chen, Luke W. Guddat, Quan Wang, Zihe Rao *, and Zhiyong Lou *. Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis. Cell. 2021, 184 (1), 184-193 e10.
